Induction of a CD 8 1 Cytotoxic T Lymphocyte Response by Cross - priming Requires Cognate CD 4 1 T Cell Help By Sally
نویسندگان
چکیده
From the * Thymus Biology Unit, The Walter and Eliza Hall Institute of Medical Research, The Royal Melbourne Hospital, Melbourne, Victoria 3050, Australia; ‡ Cooperative Research Centre for Vaccine Technology at the Queensland Institute of Medical Research, The Royal Brisbane Hospital, Herston, QLD 4029, Australia; and § The Monash Medical School, Alfred Hospital, Prahran, Victoria 3181, Australia
منابع مشابه
Induction of a CD8+ Cytotoxic T Lymphocyte Response by Cross-priming Requires Cognate CD4+ T Cell Help
Class I-restricted presentation is usually associated with cytoplasmic degradation of cellular proteins and is often considered inaccessible to exogenous antigens. Nonetheless, certain exogenous elements can gain entry into this so-called endogenous pathway by a mechanism termed cross-presentation. This is known to be effective for class I-restricted cytotoxic T lymphocyte (CTL) cross-priming d...
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